Oxidase-like activity of polymer-coated cerium oxide nanoparticles.
نویسندگان
چکیده
Inorganic enzyme? Ceria nanoparticles exhibit unique oxidase-like activity at acidic pH values. These redox catalysts can be used in immunoassays (ELISA) when modified with targeting ligands (see picture; light blue and yellow structures are nanoparticles with attached ligands). This modification allows both for binding and for detection by the catalytic oxidation of sensitive colorimetric dyes (e.g. TMB).
منابع مشابه
Antibacterial Activity of Polymer Coated Cerium Oxide Nanoparticles
Cerium oxide nanoparticles have found numerous applications in the biomedical industry due to their strong antioxidant properties. In the current study, we report the influence of nine different physical and chemical parameters: pH, aeration and, concentrations of MgSO(4), CaCl(2), KCl, natural organic matter, fructose, nanoparticles and Escherichia coli, on the antibacterial activity of dextra...
متن کاملEvaluation of Antioxidant and cytotoxic Effects of Cinnamon-Coated Cerium Oxide Nanoparticles on PC12 Cell Line
Background & objectives: Research on intelligent nanomaterials that accelerate the process of nerve regeneration and treatment by different methods such as antioxidant effects, stimulation of nerve cell proliferation, modulation of the immune system and inflammatory factors is great importance. The aim of this study was to prepare cinnamon-coated cerium oxide nanoparticles and evaluate its anti...
متن کاملInteractions between sub-10-nm iron and cerium oxide nanoparticles and 3T3 fibroblasts: the role of the coating and aggregation state.
Recent nanotoxicity studies revealed that the physico-chemical characteristics of engineered nanomaterials play an important role in the interactions with living cells. Here, we report on the toxicity and uptake of cerium and iron oxide sub-10-nm nanoparticles by NIH/3T3 mouse fibroblasts. Coating strategies include low-molecular weight ligands (citric acid) and polymers (poly(acrylic acid), M(...
متن کاملPreparation of polymer coated superparamagnetic Iron Oxide (Fe3O4) nanoparticles for biomedical application
Biomedical applications of superparamagnetic iron oxide nanoparticles (SPIONs) requiring precise control over their physical and magnetic properties, and proper surface treatment. Here we report a practical and effective electrochemical strategy for preparation of the polymer coated SPIONs. In this strategy, in situ polymer coating on the surface of SPIONs was achieved through electrodeposition...
متن کاملPreparation of polymer coated superparamagnetic Iron Oxide (Fe3O4) nanoparticles for biomedical application
Biomedical applications of superparamagnetic iron oxide nanoparticles (SPIONs) requiring precise control over their physical and magnetic properties, and proper surface treatment. Here we report a practical and effective electrochemical strategy for preparation of the polymer coated SPIONs. In this strategy, in situ polymer coating on the surface of SPIONs was achieved through electrodeposition...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Angewandte Chemie
دوره 48 13 شماره
صفحات -
تاریخ انتشار 2009